Hi Jim
You can definitely use a random orbit sander. A number of us here are using the Festool ETS-125. I like it for a number of reasons.
1) The surface it leaves is better than the surface left by my Porter Cable. The surface after using 150 feels like what my Porter Cable would leave with 220.
2) The base uses a reinforced rim, so the surface you get is nice and level. You can sand around the edges without worrying about rounding them over.
3) The dust collection, even with a bag, is second to none. With the vacuum (I have the Festool MIDI), there isn't a trace of dust in the air.
4) The paper is long lasting and less expensive than the 3M paper I'd buy at the hardware store.
And there are probably a few others I'm not thinking of